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Traditionally, the evaluation of cardiac function has focused on systolic function, however, there is a growing appreciation for the contribution of diastolic function to overall cardiac health. Given the emerging interest in evaluating diastolic function in all models of heart failure, there is a need for sensitivity, accuracy, and precision in the hemodynamic assessment of diastolic function. Hemodynamics measures cardiac pressures in vivo - offering a direct assessment of diastolic function. In this review, we summarize the underlyi