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The targets of this adaptive selection are likely regulatory sequences responsible for the increased expression of these genes, which would allow a fine-tuned physiological regulation to maintain homeostasis and thrive at CO2 seeps. Our findings reveal that standing genetic variation in DNA sequences regulating the expression of genes in response to a reduced-pH environment could provide for adaptive potential to near-future ocean acidification in fishes. Moreover, with this study we provide a forthright methodology combining transcripto