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Technology is changing the way organizations and their employees need to accomplish their work. Empirical evidence on this topic is scarce. The aim of this study is to provide an overview of the effects of technological developments on work characteristics and to derive the implications for work demands and continuous vocational education and training (CVET). The following research questions are answered What are the effects of new technologies on work characteristics? What are the implications thereof for continuous vocational education

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In Part B, 13 of 15 enrolled patients had high-grade NETs. Of these, one had PR, and four had SD for more than 10 months. The combination of alisertib and nab-paclitaxel has manageable side-effect profile and showed promising preliminary efficacy in high-grade NETs, warranting further testing. ClinicalTrials.gov identifier NCT01677559. ClinicalTrials.gov identifier NCT01677559. Chondroprogenitors display promise for articular cartilage regeneration. It is imperative to standardize culture conditions, to further e