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How to Choose the Best ADHD Medication for Adults The stimulants like methylphenidate and amphetamine boost and balance brain chemicals. Doctors typically prescribe them in the form of pills, liquids or patches. Healthcare professionals also take drugs called norepinephrine reuptake inhibitors and alpha-2 agonists for treating ADHD. These are usually used "off-label" for this purpose, since they're FDA-approved for treating other conditions. Stimulants Stimulants are the most commonly prescribed ADHD drugs. They increase the levels of brain