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This paper describes two experiments conducted to investigate changes in the autonomic nervous system and axillary temperature caused by electric potential therapy. The former was investigated using a frequency analysis of successive heartbeats (RR intervals) and cortisol in saliva. The experimental results on the RR intervals suggest no significant change in the autonomic nervous system, but those on the saliva cortisol indicate a change in the system during the therapy. The axillary temperature showed a significant increase. The resul