https://2pcpainhibitor.com/nee....d-for-organized-prop
Sleep-active neurons depolarize during sleep to suppress wakefulness circuits. Wake-active wake-promoting neurons in turn power down sleep-active neurons, therefore developing a bipartite flip-flop switch. Nonetheless, how sleep is switched on is confusing because it is as yet not known how wakefulness is translated into sleep-active neuron depolarization once the system is defined to sleep. Making use of optogenetics in Caenorhabditis elegans, we solved the presynaptic circuit for depolarizat