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egions and the executive functioning and attention domains. These findings indicate that each biomarker may independently contribute to cognitive impairment in AD.Objective To investigate positioning error analysis of the Fraxion localization system in the intracranial stereotactic radiotherapy of tumors. Methods 64 patients were divided into two groups a control group (36 patients with the standard thermoplastic mask) and a model group (28 patients with the Fraxion localization system). 3D images of the treated position were obtained b