https://www.selleckchem.com/pr....oducts/ldn193189.htm
All trials revealed a moderate risk of bias. CONCLUSION Based on current evidence, PRP injections may reduce pain more effectively than placebo injections in TMJ OA at 6 months (level of evidence moderate) and 12 months (level of evidence moderate) postinjection. This significant difference in pain reduction could also be seen when PRP was compared to hyaluronic acid at 12 months postinjection (level of evidence low). It can be cautiously interpreted that PRP has a beneficial effect on the relief of TMJ OA pain. Large-scale, low-bias