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Medication For ADHD - What Are the Side Effects? Many people suffering from ADHD have their symptoms improved by taking medication. But every person reacts differently to different medications, and side effects can be troublesome. Methylphenidate is a stimulant. It works by raising levels of a chemical in the brain that aids in controlling the behavior and attention. Stimulant medication Stimulant medications improve attention and concentration in 70 to the 80% of children and adults who take them. They affect neur