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In this research, we applied an optimization framework to spot circulation techniques that will have decreased COVID-19 relevant morbidity and mortality. Through the very first half 2021 within the condition of Missouri, enhanced vaccine allocation could have decreased instance incidence by 8% with 5926 less COVID-19 situations, 106 fewer deaths, and 4.5 million dollars in health care cost saved. As COVID-19 alternatives continue to be identified, while the odds o
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