https://www.selleckchem.com/pr....oducts/acalabrutinib
25 ± 13.65-237.54 ± 24.7 µM against BChE. Molecular docking studies were performed to investigate the binding modes and interaction energies of the (2-6) complexes with the hCA I (PDB ID1BMZ), hCA II (PDB ID2ABE), AChE (PDB ID4EY6) and BChE (PDB ID2PM8).Hutchinson-Gilford progeria syndrome (HGPS) is a premature aging disorder caused by a mutation of lamin A, which contributes to nuclear architecture and the spatial organization of chromatin in the nucleus. The expression of a lamin A mutant, named progerin, leads to functional and
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