https://www.selleckchem.com/pr....oducts/nsc-23766.htm
Only one elephant had clinically significant hypoxemia characterized by a partial pressure of oxygen (PaO2) 50 mm Hg), although pH and peripheral capillary oxygen saturation fell within acceptable ranges. None of the elephants reacted to moderately painful stimuli while sedated. The combination was reversed with intramuscular injections of naltrexone (1 mg for every 1 mg butorphanol) and atipamezole (5 mg for every 1 mg medetomidine). Recovery was smooth and calm in all the animals. Time from injection of the reversals until the first