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9-2.6), ≥ 75 years old (frail OR 1.8, 95% CI 1.3-2.4; prefrail OR 1.5, 95% CI 1.3-1.8), non-smokers (frail OR 1.6, 95% CI 1.3-2.0; prefrail OR 1.4, 95% CI 1.2-1.5), had CCI ≥ 2 (frail OR 5.1, 95% CI 2.1-12.6; prefrail OR 2.1, 95% CI 1.2-3.8), and with low household income (frail OR 4.0, 95% CI 2.8-5.8; prefrail OR 2.7, 95% CI 2.2-3.3). This study revealed a significant association between PM2.5 exposure and frailty, with a stronger effect in vulnerable groups.Precise measurement of axial length before cataract surgery is necessary for the