https://www.selleckchem.com/pr....oducts/gsk2643943a.h
The protective effects of epigallocatechin gallate (EGCG) on interleukin-1β (IL-1β)-induced apoptosis were investigated in murine MIN pancreatic β-cells. The role of uncoupling protein-3 (UCP ) signaling in this process was also explored. After treatment with IL-1β and EGCG, cells were collected and analyzed. Cell viability was measured using the CCK assay and the function of β-cells was evaluated by analyzing insulin secretion. Detection of mitochondrial function in cells was performed by measuring mitochondrial membrane potential,