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What Happens If ADHD is Left Untreated in Adults? Adults with ADHD can experience a range of problems if the condition goes untreated. This includes issues with work, relationships and mental health. Adults with untreated ADHD typically have low self-esteem and a pessimistic outlook on the world. This can make them feel as if they are failures at home and work. Inattention or lack of Focus It is normal to experience difficulty focusing from time to time, especially after a busy day at school or work. If you are noticing that your ability to focus is getting w