https://www.selleckchem.com/pr....oducts/jnj-64619178.
The expression of miR-19a declined substantially in DR rats injected with miR-19a inhibitor (P less then 0.05). RGCs were arranged regularly, showing apoptosis and milder necrosis in miR-19a inhibitor group. The proportion of apoptotic cells was substantially decreased in miR-19a inhibitor group (P less then 0.05). It was found that miR-19a inhibitor group exhibited an evidently lower protein expression of PTEN and a higher activation degree of the Akt pathway than DR group (P less then 0.05). MiR-19a binds to PTEN protein in a tar
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