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Classifiers of ensemble learning performed well in both screening and early detection model, with an accuracy range of 0.817-0.987. Classical classifiers showed relatively worse performance. Besides, the ensemble algorithm type and silicosis cases inclusion had no significant effect on classification (p 0.05). There was no connection between personal smoking habits and classification accuracy. Breath tests based on an e-nose consisted of 16× sensor array performed well in silicosis screening and early detection. Raw data input showed