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Both the number of deaths and that of severe cases showed a significant correlation (R .57 and .41, with P.01) with the P/T ratio. Deaths and severe cases were associated with higher mean personal income and lower density of General Practioners (GPs). The association of P/T with severe cases and deaths retained statistical significance after adjusting for mean personal income (R .30 and .41, respectively; both P=.04) and GPs density (R .21 and .19, respectively; both P=.03). A more aggressive screening strategy for SARS-Cov-2, was associated

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Common reasons for negative scientific review of LOIs included investigator inexperience, perceived lack of major scientific impact, lack of preliminary data and flawed or confused experimental design, while the most common reasons for negative reviews of final proposals included questions of scientific impact and issues of study design, including outcome measures, randomization, and stratification. Completed projects have been published in high impact clinical journals. Findings highlight several factors leading to successfully obtain