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Health Issues That Affect German Shepherd Life Expectancy German Shepherds are in their peak between 2 and 6. The German Shepherd is at its best in terms of mental and physical ability. Their large size puts them at a greater risk of developing cancer musculoskeletal issues, and other health conditions that can have a negative impact on their lives. German Shepherds in the working line often live more active lives than their show line counterparts. They require a diet that is rich i