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05) and reduced levels after 12 months compared to baseline (p = 0.013) in patients without EDSS progression for 12 months. In this explorative observational study, our data suggest that the longitudinal measurement of serum NfL may be useful in addition to MRI to monitor disease activity and therapy response.The global digital elevation model (DEM) is important for various scientific applications. With the recently released TanDEM-X 90-m DEM and AW3D30 version 2.2, the open global or near-global coverage DEM datasets have been furth