https://www.selleckchem.com/pr....oducts/etomoxir-na-s
Viewing different TWAS methods from an MR perspective provides us a unique angle for understanding their benefits and pitfalls. We systematically introduce the MR analysis framework, explain how features of the GWAS and expression data influence the adaptation of MR for TWAS, and re-interpret the modeling assumptions made in different TWAS methods from an MR angle. We finally describe future directions for TWAS methodology development. We hope that this review would serve as a useful reference for both methodologists who develo