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9years median follow-up, 51 patients (32.7%) developed CAV or revascularization of which 8 received at least a second revascularization, 3 were re-transplanted, and 9 died from CAV-related causes. Analysis showed a significant increased CAV-risk among depressed patients (HR=2.27 [1.10-4.69], p=.026), even in adjusted models (HR=2.25 [1.01-4.98, p=.047). Depressive symptoms at 1-year post-HTx unfavorably impact mortality and CAV, highlighting the need for interventions. Depressive symptoms at 1-year post-HTx unfavorably impact mortality an
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