https://www.selleckchem.com/CDK.html
The enantioselective synthesis of bis-homoallylic alcohols through nickel-catalyzed three-component fragment couplings of simple aldehydes, dienes, and aryl organoborons is disclosed. The reactions proceed through diene dicarbofunctionalization that concurrently forms two C-C bonds and two stereogenic centers. The transformations are promoted by a 5.0 mol % loading of a readily accessible chiral phosphine-nickel complex and afford products with high stereoselectivity.Objective.Due to the variability of human movements, muscle activations vary among
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