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Necrotizing lymphadenitis is arare disease. It is often misdiagnosed because of the lack of typical clinical manifestations. It is worth noting that necrotizing lymphadenitis may be aprecursor lesion of systemic lupus erythematosus or tumours, so regular follow-up is needed to facilitate early diagnosis. Here, we report acase and conduct aliterature analysis summarizing the clinical features of necrotizing lymphadenitis and its treatment and management practices. A16-year-old young woman presented with fever and lymphadenopathy as the