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For Adults UK The use of medicines can reduce symptoms and make it easier to complete tasks. They can also help with issues that are underlying, such as depression, insomnia, anxiety and. Stimulants (methylphenidate and the more recent amphetamine based medication Lisdexamfetamine) are the first line treatment for adults suffering from ADHD. They increase the levels two chemical messengers found in the brain, which improve focus and decreases