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Conditions that would prompt a switch from PVA to an alternate method of venous access include loss of venous access, patient preference, or development of a requirement for very frequent treatment over a long period of time. CONCLUSIONS While PVA is not suitable for all patients requiring TPE, it has significant safety advantages over other approaches and should be employed whenever possible. © 2020 Wiley Periodicals, Inc.PURPOSE To construct longitudinal fetal reference ranges for global longitudinal myocardial deformatio