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TYK2 is a potential target in ESCC, and cirsiliol could inhibit ESCC by suppression of TYK2. TYK2 is a potential target in ESCC, and cirsiliol could inhibit ESCC by suppression of TYK2. To develop an effective model of predicting fatal outcomes in the severe coronavirus disease 2019 (COVID-19) patients. Between February 20, 2020 and April 4, 2020, consecutive confirmed 2541 COVID-19 patients from three designated hospitals were enrolled in this study. All patients received chest computed tomography (CT) and serological examinations at ad