https://www.selleckchem.com/pr....oducts/Adrucil(Fluor
Cognitive impairment in the late stage of traumatic brain injury (TBI) is associated with the NOD-, LRR and pyrin domain-containing protein 3 (NLRP3) inflammasome, which plays an important role in neuroinflammation. Although classical inflammatory pathways have been well-documented in the late stage of TBI (4-8weeks post-injury), the mechanism by which the NLRP3 inflammasome impairs cognition is still unclear. Mice lacking the gene encoding for NLRP3 (NLRP3-knockout mice) and their wild-type littermates were used in a cont