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01), generation of free radicals in the leukocytes (+70%, 0.05), dialysate level of elastase (+102%, 0.01), tumor necrosis factor α (+48%, 0.01) and monocyte chemoattractant protein-1 (+42%, 0.01). Drained dialysate volume was lower (-21%, 0.01) and peritoneal permeability increased in rats with colitis (+55%, 0.01). In animals with the hyaluronan supplemented dialysis fluids, the intensity of the intraperitoneal inflammation was reduced. Visceral inflammation during colitis induces the inflammatory reactio