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98; P=0.98), and primary BSI (2.54 vs. 3.42 catheter days; HR0.79; P=0.67). CHG-impregnated dressing significantly decreased the incidence of catheter colonization (3.82 vs. 7.59 per 1000 catheter days; HR0.40; P=0.04). In both groups, the most frequent microorganisms isolated in CLABSI or catheter colonization were gram positive bacteria (the majority were coagulase-negative staphylococci). The use of CHG-impregnated dressing does not decrease CLABSI incidence in critically ill pediatric patients, but it significantly reduced catheter co