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To facilitate the data interpretation, positive and negative polarity ToF-SIMS image data were transformed into a single hyperspectral data set and analyzed using principal component analysis. The combination of a novel protocol and the use of multivariate data analysis allowed us to discover new marker ions that are attributable to leucodopachrome, a metabolite specific to the biosynthesis of eumelanin. The described methodology may be adapted for the investigation of other classes of molecules in frozen tissues from zebrafish and other

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Bifold Door Seal Repair Bifold doors integrate door panels into concertinaed tracks to open and close a space. In time, they can suffer from a number of common issues that require professional attention. Inadequate maintenance can cause your bifold door to jam which can lead to hardware issues and jammed doors. To prevent this from happening it is recommended to lubricate your bifold doors every few weeks. Seals that are becoming less durable Seals on bifold