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The increasing water pollution caused by the presence of nano- and microplastics has shown a need to pursue solutions to remediate this problem. In this work, an extracellular polymeric substance (EPS) producing freshwater Cyanothece sp. strain was exposed to nano- and microplastics. The bioflocculant capacity of the biopolymer produced was evaluated. The influence of different concentrations (1 and 10 mg L-1) of polystyrene nano- and microplastics in the extracellular carbohydrates and in the EPS production was studied. The presence of