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9% (95% confidence interval (CI) 75.4-92.4%, = 25.18%), pooled complications rate was 29.1% (95% CI 18.6-42.3%, = 50.40%). Subgroup analysis was performed based on ablation methods, which showed clinical success rate for radiofrequency ablation (RFA) was 83.5% (95% CI 67.9-92.4%), and 87.9% (95% CI 66.2-96.4%) for ethanol ablation (EA). In terms of complications rate, it was 32.2% (95% CI 19.4-48.4%) for RFA, and 21.2% (95% CI 6.8-49.9%) for EA. EUS-guided ablation therapy is a promising alternative treatment for solid pancreatic tum