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To report our experience of percutaneous image-guided cryoablation of renal tumors located within 10mm of the pyeloureteric junction (PUJ) and/or ureter, with hydrodissection as a stand-alone thermoprotective technique. All patients who were offered combined hydrodissection and cryoablation of the PUJ/ureter to treat stage-1 renal cell carcinoma were retrospectively reviewed. Data regarding patients, lesions, and outcomes were collected. Twenty tumors in 20 patients (13 males7 females) with a mean age of 74.4 ± 7.5 were included. Mean t