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4.1; R Foundation for Statistical Computing, Vienna, Austria) software will be used for all statistical analyses. This study will provide a high-quality synthesis to examine the prevalence and associated factors of ocular trauma worldwide. Furthermore, current study will project disease estimates in the next 50 years. This systematic review and meta-analysis will provide first evidence to evaluate the burden of ocular trauma in the general population. This systematic review and meta-analysis of randomized controlled trials does not req