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The aim of this study was to assess the effect of vibration stimulation application in ventrogluteal region on intramuscular injection pain and patient satisfaction. Intramuscular injection pain caused distress for the patients and affected their compliance with the treatment. This was a prospective, single-blind, cross-over study. The study complied with the guidelines of Consolidated Standards of Reporting Trials (CONSORT). Eighty-four patients who applied to the adult emergency department received an intramuscular injection of amoxic