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The goal of this study would be to compare the long-lasting cognitive, motor, and behavioral effects of preterm infants pre and post the utilization of a pain and sedation protocol. In inclusion, we investigated perhaps the enhanced opiate administration resulting following the implementation process had an impact on these outcomes. Practices intellectual results had been evaluated utilising the Kaufman Assessment Battery for the kids (KABC), neuromotor exams were considering Amiel-Tison