https://www.selleckchem.com/products/stx-478.html
mbrane surface charge alterations are involved in histone-induced barrier dysfunction and tight junction disruption. Extracellular histones cause a reversible, region-specific increase in BBB permeability to small molecules by disrupting tight junctions in the hippocampus. We suggest that circulating histones may contribute to cerebrovascular injury or brain dysfunction by altering BBB structure and function. Extracellular histones cause a reversible, region-specific increase in BBB permeability to small molecules by disrupting tight ju

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