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In inclusion, the discerning separation of UO2 2+ and Th4+ ions one of the competitive ions of similar chemical properties were additionally examined. The ionophore immobilized C18 silica monolith columns demonstrated a varying degree of retention behavior for UO2 2+ and Th4+ ions (UO2 2+ is retained longer than Th4+ under all analytical problems), fundamentally causing rapid separations within a period of ≤5 min. A 0.1 M option of 2-hydroxyisobutyric acid (HIBA, 1 mL mi