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66, p0.0001) and at 21 dpi (R=-0.65, p0.0001), as well as age and numbers of worms at 21 dpi (R=0.74, p0.0001). The relative weight of the thymus, lungs and small intestines were higher in rats at 2 and 3mo in comparison to the older groups of rats. Aging process interfered on host-parasite relationship and changed the dynamics of infection of S. venezuelensis in Wistar rats. Aging process interfered on host-parasite relationship and changed the dynamics of infection of S. venezuelensis in Wistar rats.Oxidative stress, a cy