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After that, the system was evaluated on a blind test set with 947 DSA sequences from 146 patients. Results Of the 354 aneurysms, 316 (89.3%) were successfully detected, corresponding to a patient level sensitivity of 97.7% at an average false positive number of 3.77 per sequence. The system runs for less than one second per sequence with an average dice coefficient score of 0.533. Conclusions This deep neural network assists in successfully detecting and segmenting aneurysms from 2D DSA sequences, and can be used in clinical practice.B