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Buy A1 and A2 Driving License Online If you pass your CBT at the age of 17, you can ride a 125cc (A1 class/11kW/15bhp) bike on L-plates. To upgrade to an A2 licence, you must go through more training and exams. The function of this step-by-step approach is to enable young individuals to get experience operating less effective bikes before moving onto more powerful machines. After 2 years, you can then upgrade to an An unlimited licence. Age R

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Polycythemia Vera (PV) is a chronic myeloproliferative neoplasm resulting from an acquired driver mutation in the JAK2 gene of hematopoietic stem and progenitor cells resulting in the overproduction of mature erythrocytes and abnormally high hematocrit, in turn leading to thromboembolic complications. Therapeutic phlebotomy is the most common treatment to reduce the hematocrit levels and consequently decrease thromboembolic risk. Here we demonstrate that, by using the iron restrictive properties of the antisense oligonucleotides agai