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ociated with worse outcomes indicates that safety during critical care transport is an important area for future quality improvement work. Afatinib has shown favorable response rates (RRs) and longer progression free survival (PFS) in lung cancer patients harboring EGFR mutations compared with standard platinum-based chemotherapy. However, serious adverse drug reactions (ADRs) limit the clinical application of afatinib. We designed a retrospective study, enrolling all patients with metastatic lung adenocarcinoma who were diagnosed and