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The same metabolites in free and glucuronidated types are additionally recommended for analytical affirmation in urine samples. Ester hydrolysis plus dehydrogenation metabolite (B2 was the second most ample major metabolite in the HLM model, similar to the in-vivo findings where it is the second most prevalent metabolite detected in 18/20 urine samples (Table 2). Ester hydrolysis with dehydrogenation formed in-vivo on this study was additionally reported amongst different indazole carboxamide ty