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We also discuss how the expression and somatic mutations of key NER genes affect the response of cancer cells to cisplatin. Finally, small molecules targeting NER factors provide important tools to manipulate NER capacity in cancer cells. The status of research on these inhibitors and their implications in cancer treatment will be discussed.Mycobacterium tuberculosis is the etiological agent of tuberculosis (T, a disease that affects millions of people in the world and that is associated with several human diseases. The bacillus is hig