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Successful treatment outcomes are best achieved through controlling diseases affecting the oral cavity and supporting structures.Design Systematic review and meta-analysis.Data sources A search of two databases, Medline and CENTRAL, was undertaken, limited to articles published in English from the oldest records until 10 July 2018.Study selection Participants included patients diagnosed with type 2 diabetes and periodontitis, with HbA1c and C-reactive protein (CRP) measurements at baseline. The intervention was surgical or non-surgical