https://histaminereceptor-sign....al.com/can-sars-cov-
CPT-11/SN38 treatment had only limited results on tumors in transgenic mice, but PEG-[SN22]4 treatment caused complete tumor regression lasting over a few months (tumor no-cost at necropsy). PEG-[SN22]4 also markedly extensive survival of mice with drug-resistant, orthotopic NB also it caused long-lasting (6+ months) remissions in 80% to 100percent of NB and sarcoma xenografts. SN22 administered as a multivalent polymeric prodrug resulted in enhanced and protracted tum
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