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60-1.06; = 0.126); 5-year disease-free survival (HR = 0.94, 95%CI = 0.73-1.22; = 0.65; abscess (OR = 1.10, 95%CI = 0.67-1.80; = 0.713), fistulae (OR = 0.79, 95%CI = 0.33-1.89; = 0.60; wound complication (OR = 1.21, 95%CI = 0.62-2.36; = 0.575); anastomotic leakage (OR = 1.09, 95%CI = 0.59-2.02; = 0.775); and neurogenic bladder dysfunction (OR = 0.69, 95%CI = 0.31-1.55; = 0.369). However, the meta-analysis of 5-year local control was significantly different (OR = 3.07, 95%CI = 1.66-5.66; = 0.00. The advantage of IORT is mainly refl