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The heat shock response (HSR) is a transcriptional program of organisms to counteract an imbalance in protein homeostasis. It is orchestrated in all eukaryotic cells by heat shock factor 1 (Hsf1). Despite very intensive research, the intricacies of the Hsf1 activation-attenuation cycle remain elusive at a molecular level. Posttranslational modifications belong to one of the key mechanisms proposed to adapt the Hsf1 activity to the needs of individual cells and phosphorylation of Hsf1 at multiple sites has attracted much attention. Acco

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Ezee Glow Celestial 60 Inch Media Wall Fire A media wall fireplace gives you the look of a genuine wood log flame, but with the added benefit of warmth and convenience. No more worrying about burning out flames that aren't working or stains from soot. Our electric fireplaces are available with a range of glass fittings. These include one-sided, three-sided and two-sided. Controlled by your smartphon