https://www.selleckchem.com/products/azd5991.html
STING-NVs repolarize immunosuppressive M2-like macrophages into antitumor M1-like macrophages in vitro and in the tumor microenvironment of melanoma. In a poorly immunogenic murine melanoma model, intralesional STING-NVs outperform liposomal CDG and fluoride-CDG for melanoma immunotherapy. These results suggest the great potential of STING-NVs for cancer immunotherapy.Cancer immunotherapy has made recent breakthrough, including immune checkpoint blockade (IC that inhibits immunosuppressive checkpoints such as programmed cell death pro